Purification of physiologically active chitosan oligosaccharides by means of nanofiltration membrane

Takashi Kuroiwa, Hiroshi Izuta, Hiroshi Nabetani, Mitsutoshi Nakajima, Seigo Sato, Sukekuni Mukataka, Sosaku Ichikawa, Takashi KUROIWA

Research output: Contribution to journalArticlepeer-review

Abstract

We used nanofiltration membranes to study the purification of physiologically active chitosan oligosaccharides (pentamers and hexamers). Calculations based on the experimental data of batch filtration suggested that the content of the target oligosaccharides in the product mixture could be improved from 30% to 77% by continuous diafiltration under optimized conditions.
Translated title of the contributionPurification of physiologically active chitosan oligosaccharides by means of nanofiltration membrane
Original languageAmerican English
Pages (from-to)336 - 341
JournalMembrane
VolumeVol. 34
Issue numberNo. 6
DOIs
StatePublished - 2009

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